Individual Variability in Physiological Responses and Psychological Conditions Associated With Methamphetamine Use: Pilot Ecological Momentary Assessment Study Using a Wearable Device and Self-Monitoring Mobile App
Notice bibliographique
Résumé
Background: Digital mental health approaches offer a novel means to monitor and reduce harms associated with substance use in daily life. However, limited evidence exists on their application for methamphetamine (MAMP) use, particularly regarding individual variability in physiological responses and psychological conditions. Objective: This pilot study aimed to explore inter- and intraindividual differences in craving, emotion, and heart rate associated with MAMP use, using data collected from a wearable device (Fitbit) and a mobile-based self-monitoring app. Methods: Participants were individuals with MAMP use disorder receiving outpatient treatment in Japan. The analysis included 7 participants who used MAMP during an 8-week observation period. Physiological data, including heart rate and sleep patterns, were collected using Fitbit devices, while daily self-reported MAMP use, craving intensity, and emotional status were recorded via a mobile app. After syncing the data, we visualized and summarized individual MAMP use patterns in detail. Correlations between physiological and psychological indicators and the frequency of MAMP use per day were analyzed. In addition, heart rate trends before and after MAMP use events were evaluated using a linear mixed effects model, and both interindividual variability and intraindividual variability were assessed. Results: Patterns of MAMP use varied widely across participants, with it most commonly occurring in the morning or at night, regardless of the day of the week. Craving and negative emotions were frequently reported on MAMP use days and were positively correlated with the number of MAMP use episodes per day. Participants who used MAMP more frequently exhibited relatively higher resting heart rates. Following MAMP use, heart rate increased significantly and remained elevated for up to 9 hours. Sleep duration and frequency were reduced or absent on MAMP use days. Approximately 64% of the variance in heart rate was attributable to interindividual differences, while 12% reflected variability across events within the same individual. Conclusions: This pilot study demonstrates the feasibility and value of using digital tools to examine physiological responses and psychological conditions associated with MAMP use in real-world settings. Persistent cardiovascular activation and disrupted sleep highlight the potential risks of long-term MAMP use. Individual differences in heart rate responses, craving, and emotional states underscore the importance of personalized intervention strategies. Integrating real-time self-monitoring, notifications for elevated heart rate, and online cognitive behavioral therapy into digital therapeutic interventions may improve health outcomes for individuals with MAMP use disorder.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,001 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,001 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».