The Contribution Of Pharmacists To Antibiotic Stewardship In Dental Practice: A Systematic Review
Notice bibliographique
Résumé
Background: Dental practice is a significant source of outpatient antibiotic prescriptions, contributing substantially to the global challenge of antimicrobial resistance (AMR). A considerable proportion of these prescriptions are inconsistent with evidence-based guidelines. Pharmacist-led antimicrobial stewardship (AMS) programs have demonstrated efficacy in other healthcare settings, but their specific contribution within dentistry is less synthesized. This systematic review aims to evaluate the role, interventions, and impact of pharmacists in promoting appropriate antibiotic use in dental practice. Objectives: To systematically review and synthesize the available evidence regarding the role and effectiveness of pharmacists and pharmacist-led interventions in dental antibiotic stewardship. Methods: A systematic search of electronic databases was conducted to identify studies evaluating pharmacist-led AMS interventions in dental settings. The review included randomized controlled trials (RCTs), non-randomized controlled trials, and observational studies. Data on study design, intervention components, and outcomes related to antibiotic prescribing were extracted and synthesized narratively. The methodological quality of included studies was assessed using the Cochrane Risk of Bias 2 (RoB 2) tool for RCTs and the Newcastle-Ottawa Scale (NOS) for observational studies. Key Findings: The evidence consistently demonstrates that pharmacist-led interventions are highly effective in improving antibiotic prescribing in dentistry. These interventions, which include educational outreach, academic detailing, audit and feedback, and collaborative guideline development, have been shown to reduce inappropriate antibiotic prescribing by approximately 70%. Pharmacists contribute essential expertise in pharmacotherapy, antibiotic spectra, and resistance patterns, filling a critical knowledge gap for many dental practitioners. Successful programs are characterized by interprofessional collaboration, institutional commitment, and data-driven feedback mechanisms. However, significant systemic barriers, including professional siloing, inadequate communication channels, educational deficiencies in dental curricula, and a lack of integrated health information systems, hinder the widespread implementation of these effective collaborations. Conclusions: There is compelling evidence that pharmacists are a critical and currently underutilized resource in advancing antibiotic stewardship in dental practice. Their involvement leads to substantial and clinically meaningful improvements in prescribing appropriateness. To fully realize this potential, systemic changes are required, including the integration of interprofessional AMS education into dental and pharmacy curricula, the development of supportive health policies and reimbursement models, and the adoption of technologies that facilitate seamless collaboration.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,008 | 0,010 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,003 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,001 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,001 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».