Abstract P2-14-02: Complications of breast reconstruction in a provincial population of breast cancer survivors
Notice bibliographique
Résumé
Abstract Background: Breast cancer is the most prevalent cancer in women in Canada. There are varying reports of the use of breast reconstruction in various populations and very few prospective trials or population reports of complications related to breast reconstruction in breast cancer patients. The goal of this study is to describe the use of breast reconstruction in breast cancer survivors in British Columbia, the risk of complications after breast reconstruction, and factors associated with a higher risk of complications. Methods: Electronic Records from the BC Cancer Agency were used to identify women diagnosed with invasive breast cancer between 2001-2008 in British Columbia. Administrative hospital records used with permission of the British Columbia Ministry of Health, obtained through PopulationData BC, were used to obtain details about all surgeries,hospital admissions and associated complications for the cohort. Analyses of reconstruction for those treated with breast-conserving surgery (BCS) versus mastectomy were done separately. For those who underwent mastectomy following BCS, complications after BCS before mastectomy were attributed to the BCS, and those that occurred after mastectomy were attributed to the mastectomy. These analyses included a description of the type of reconstruction procedures used in this era, and the frequency and types of complications after the reconstruction procedures. Logistic regression was used to identify risk factors for complications post reconstruction. Results: The cohort consisted of 18,642 women; 4868 had mastectomy alone, 8633 had BCS alone, 2894 had both, and 2247 had neither surgery. Of those undergoing BCS (11527), 746 had reconstructive procedures. Most of these were separate procedures; 55% were ≤50 years of age. The most common complication was "miscellaneous complication of internal prosthetic devices, implants or grafts". One hundred eight (14%) of those with reconstruction after BCS had complications within 30 days of the reconstruction procedure, 134 (18%) had complications within one year of the procedure. Of those undergoing mastectomy (7762), 7497 had their mastectomies within 1 year of diagnosis. Ninety-six had bilateral mastectomies. 1766 underwent reconstructive procedures; 74% were immediate procedures, 57% were ≤ 50 years of age. The most common complication was "miscellaneous complication of internal prosthetic devices, implants or grafts". One hundred sixty-seven (9%) of those with reconstruction after (or with) mastectomy had complications within 30 days of the reconstruction procedure, 227 (13%) had complications within one year of the procedure. Regression analysis showed that no radiotherapy (OR=0.65) and premenopausal status (OR=0.70) were significantly associated with a lower risk of complication post reconstruction. Conclusion: Complications related to reconstructive procedures for breast cancer happened in the minority of breast cancer survivors. They were more common in those with BCS, and were more likely for those who underwent adjuvant radiotherapy or were postmenopausal. Citation Format: Elaine S Wai, Ling Hong Lu, Cheryl Alexander, Mary L Lesperance, Mary L McBride, Scott Tyldesley, Chris Taylor. Complications of breast reconstruction in a provincial population of breast cancer survivors [abstract]. In: Proceedings of the Thirty-Seventh Annual CTRC-AACR San Antonio Breast Cancer Symposium: 2014 Dec 9-13; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2015;75(9 Suppl):Abstract nr P2-14-02.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,001 |
| Bibliométrie | 0,001 | 0,003 |
| Études des sciences et des technologies | 0,002 | 0,000 |
| Communication savante | 0,001 | 0,000 |
| Science ouverte | 0,001 | 0,001 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,003 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».