CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
2006· article· en· Nature Genetics· Medicine
affsans résumé
1 985
citations
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Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004· article· en· Nature· Medicine
affsans résumé
1 948
citations
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
2001· article· en· Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
1 873
citations
MicroRNA: Biogenesis, Function and Role in Cancer
2010· article· en· Current Genomics· Biochemistry, Genetics and Molecular Biology
aff
1 835
citations
Rational design of cationic lipids for siRNA delivery
2010· article· en· Nature Biotechnology· Biochemistry, Genetics and Molecular Biology
affsans résumé
1 779
citations
Polyploidy and genome evolution in plants
2005· review· en· Current Opinion in Plant Biology· Agricultural and Biological Sciences
affsans résumé
1 364
citations
Argonaute proteins: key players in RNA silencing
2007· review· en· Nature Reviews Molecular Cell Biology· Biochemistry, Genetics and Molecular Biology
affsans résumé
1 362
citations
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
2005· article· en· Nature Biotechnology· Biochemistry, Genetics and Molecular Biology
affsans résumé
1 252
citations
RNAi-Mediated Targeting of Heterochromatin by the RITS Complex
2004· article· en· Science· Biochemistry, Genetics and Molecular Biology
aff
1 239
citations
Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**
2012· article· en· Angewandte Chemie International Edition· Biochemistry, Genetics and Molecular Biology
afffund
1 221
citations
The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2
2007· article· en· Nature Medicine· Engineering
affsans résumé
1 141
citations
Lipid Nanoparticle Systems for Enabling Gene Therapies
2017· review· en· Molecular Therapy· Biochemistry, Genetics and Molecular Biology
afffundabout
1 120
citations
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
2012· review· en· Nature Structural & Molecular Biology· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
1 044
citations
RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond
2013· review· en· Nature Reviews Genetics· Agricultural and Biological Sciences
fundno affsans résumé
968
citations
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
2003· article· en· Nature Genetics· Neuroscience
affsans résumé
934
citations
Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer
2009· article· en· Cancer Research· Medicine
fundno aff
862
citations
Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity
2016· article· en· Cell Death and Differentiation· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
855
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EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
2013· article· en· Cancer Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
841
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Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions
2007· review· en· Nature Reviews Genetics· Biochemistry, Genetics and Molecular Biology
fundno affsans résumé
791
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Dll1+ secretory progenitor cells revert to stem cells upon crypt damage
2012· article· en· Nature Cell Biology· Medicine
affsans résumé
789
citations
Fragile X syndrome
2017· review· en· Nature Reviews Disease Primers· Biochemistry, Genetics and Molecular Biology
affsans résumé
779
citations
Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses
2016· article· en· European Heart Journal· Biochemistry, Genetics and Molecular Biology
afffund
768
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Short RNAs Repress Translation after Initiation in Mammalian Cells
2006· article· en· Molecular Cell· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
736
citations
Global Transcription in Pluripotent Embryonic Stem Cells
2008· article· en· Cell stem cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
698
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LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
2018· article· en· Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
679
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