The Link Between Plasma 25-Hydroxyvitamin D and Lung Function in General and Asthmatic Children
Bibliographic record
Abstract
Vitamin D has been shown to play an important role in many bodily functions including the proper functioning of the respiratory system in adults. However, very little epidemiological evidence is available examining the relationship between vitamin D and pulmonary function among children. Our study examined the association between plasma 25-hydroxyvitamin D [25(OH)D] and pulmonary function in children. We used cross-sectional data from 1,421 children aged 6–17 years who participated in the Canadian Health Measures Survey (CHMS) in 2007–09. Multiple linear regression analysis was used to examine the association in the general children population and children with asthma. The data showed that 20% of children had plasma 25(OH)D concentration below 50 nM, which is classified as deficient. Linear regression analysis showed no significant association between 25(OH)D and lung function testing variables after adjustment for confounding factors in the general children population. However, data demonstrated a positive association of plasma 25(OH)D with FEV 0.75 , FEV 1 , and FEV 1 /FVC among boys with asthma. In summary, there was no significant relationship between plasma 25(OH)D and pulmonary function among the general children population; however, in boys with asthma, plasma 25(OH)D had a positive relationship with respiratory function.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".