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Record W1191423293 · doi:10.2174/1874285801105010127

Respiratory Syncytial Virus Infection in High-Risk Infants

2011· editorial· en· W1191423293 on OpenAlexaboutno aff
Bernhard Resch

Bibliographic record

VenueThe Open Microbiology Journal · 2011
Typeeditorial
Languageen
FieldMedicine
TopicRespiratory viral infections research
Canadian institutionsnot available
Fundersnot available
KeywordsPalivizumabMedicineDiseasePediatricsPopulationIntensive care medicineVirusImmunologyInternal medicineEnvironmental health

Abstract

fetched live from OpenAlex

Respiratory syncytial virus (RSV) is the most important cause of lower respiratory tract infection (LRTI) in infants and children and is associated with substantial morbidity in both inpatient and outpatient settings. Overall RSV is associated with 20 % of hospitalizations, 18 % of emergency department visits and 15 % of office visits for acute respiratory infections from November trough April Bronchiolitis hospitalizations in children younger than 2 years old significantly increased from 3.3% in 2002 to 5.5% in 2007, mainly because of RSV infections in US In Canada, inpatient care of RSV illness costs $ 18 million (US dollars) yearly, accounting for 62 percent of the total cost of this disease The magnitude of the costs is understandable, since virtually all children become infected with RSV within two years after birth, and one percent requires hospitalization Recurrent wheezing following serious RSV associated LRTI is a common phenomenon of the disease that might persist until adulthood This Supplement of the Open Microbiology Journal focuses on that topic by a couple of review articles that represent a general clinical view. Therese Popow-Kraupp and Judith Aberle from the Institute of Clinical Virology of the Medical University of Vienna evaluate diagnostic tests for the detection of RSV including RSV rapid antigen detection tests from several specimen, nucleic acid assays and RTmultiplex PCRs as future trends. This chapter is followed by a review on the epidemiology of RSV infection in preterm infants by Bernhard Resch and Stefan Kurath from Austria and Paolo Manzoni from Italy. Especially due to the development of the humanized monoclonal antibody palivizumab that provides immunoprophylaxis against RSV when given monthly over the RSV season in high-risk

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesResearch integrity, Insufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.360
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0020.009
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.371
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designNot applicable
Domainnot available
GenreEditorial

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2011
Admission routes1
Has abstractyes

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