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Record W124413104

DNA computers: tomorrow's reality

2001· book· en· W124413104 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueWorld Scientific Publishing Co., Inc. eBooks · 2001
Typebook
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDNA and Biological Computing
Canadian institutionsWestern University
Fundersnot available
KeywordsMathematical and theoretical biologySimple (philosophy)Mathematical problemComputer scienceMathematicsMathematical structureField (mathematics)Theoretical computer scienceBiologyPure mathematicsBioinformaticsMathematics educationEpistemology
DOInot available

Abstract

fetched live from OpenAlex

The field usually referred to as mathematical biology is a highly interdisciplinary area that lies at the intersection of mathematics and biology. Classical illustrations include the development of stochastic processes and statistical methods to solve problems in genetics and epidemiology. As the name used to describe work in this field indicates, with “biology” the noun, and “mathematical” the modifying adjective, the relationship between mathematics and biology has so far been one–way. Typically, mathematical results have emerged from or have been used to solve biological problems (see [24] for a comprehensive survey). In contrast, Leonard Adleman, [1], succeeded in solving an instance of the directed Hamiltonian path problem solely by manipulating DNA strings. This marks the first instance of the connection being reversed: a mathematical problem is the end toward which the tools of biology are used. To be semantically correct, instead of categorizing the research in DNA computing as belonging to mathematical biology, we should be employing the mirror–image term biological mathematics for the field born in November 1994. Despite the complexity of the technology involved, the idea behind biological mathematics is the simple observation that the following two processes, one biological and one mathematical, are analogous: (a) the very complex structure of a living being is the result of applying simple operations (copying, splicing, etc.) to initial information encoded in a DNA sequence, (b) the result f(w) of applying a computable function to an argument w can be obtained by applying a combination of basic simple functions to w (see Section 4 or [42] for details). If noticing this analogy were the only ingredient necessary to cook a computing DNA soup, we would have been playing computer games on our DNA laptops a long time ago! It took in fact the ripening of several factors and a

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Scholarly communication
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.035
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0050.000
Open science0.0020.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.269
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it