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Record W132677512 · doi:10.1096/fasebj.21.5.a57-b

Effectiveness of a vegan based high soy protein diet on weight loss and serum lipids

2007· article· en· W132677512 on OpenAlexaff
Julia MW Wong, Cyril W.C. Kendall, Amin Esfahani, Vivian Ng, Kathryn A. Greaves, Greg Paul, David J.A. Jenkins

Bibliographic record

VenueThe FASEB Journal · 2007
Typearticle
Languageen
FieldMedicine
TopicDiet and metabolism studies
Canadian institutionsUniversity of TorontoSt. Michael's Hospital
Fundersnot available
KeywordsVegan DietWeight lossBlood lipidsSoy proteinOverweightObesityMetabolic syndromeBody weightMedicineInternal medicineEndocrinologyCarbohydrateAnimal scienceFood scienceChemistryCholesterolBiology

Abstract

fetched live from OpenAlex

Background: High protein, low carbohydrate diets have focused on animal protein sources, but their associated saturated fat may result in undesirable blood lipid effects. Objective: To assess the effectiveness of a vegan based high soy protein diet on body weight and blood lipids, under metabolic and real‐world conditions. Method: 44 overweight hyperlipidemic subjects (18M, 26F; 56.2±7.5y; 31.1±2.6kg/m2; LDL 4.07±1.21mmol/L) took either a vegan based high protein diet (vegan) or a low fat (NCEP Step 2) control. Subjects consumed 60% of their estimated energy requirements during the 1‐month metabolic phase and were advised to follow their respective diet for an additional 6 months ad libitum. 23 participants completed both phases. Results: On the metabolic phase, both NCEP and vegan diets resulted in weight loss (−5.1±0.2%, P<0.005; −4.9±0.4%, p<0.005; respectively) and total:HDL‐C reductions (−6.4±2.8%, P=0.046; −19.2±6.5%, P=0.002; respectively). At the end of the ad libitum phase, body weight reduction on the NCEP and vegan diets, compared to baseline, were −6.6±1.0% (P<0.005) and −7.3±1.2% (P<0.005) and total:HDL‐C were −3.4±2.6% (P=0.127) and −10.1±.3.2% (P=0.005), respectively. Conclusion: Under real‐world conditions, a high soy protein vegan diet appears to improve the blood lipid profile compared to a NCEP diet despite similar weight reductions. Research support: The Solae Company

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.253
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2007
Admission routes1
Has abstractyes

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