Corticosteroid-related psychiatric complications in the treatment of Hodgkin's lymphoma in an adolescent.
Bibliographic record
Abstract
We present the case of an adolescent with Hodgkin’s Lymphoma, who developed symptoms of psychosis and mania during his treatment. Psychiatric side-effects of corticosteroids in the adult population have long been recognized and documented. A wide range of mental status changes have been reported (Francois Sirois, 2003). However, case reports documenting psychosis or mania related to corticosteroid use in children are rare. Psychotic symptoms developing during the treatment of asthma have been described, sometimes with mood disorder symptoms (French et al, 2003, Couturier et al, 2001, and Dawson and Carter, 1998). Beshay and Pumariega (1998) presented the case of a boy treated for ulcerative colitis, who developed depressive and psychotic symptoms. There are also published cases of adolescents with Acute Lymphoblastic Leukemia developing psychotic symptoms during treatment with corticosteroids (Ducore et al, 1983, Kramer and Cottingham, 1999, Sutor et al, 1996). Our case adds to the literature involving steroid-induced psychosis and mania in an adolescent with cancer.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".