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Characteristics and Outcomes of Double Outlet Left Ventricle

2010· article· en· W1490145865 on OpenAlexaff
Carolin Imai-Compton, Maryam Elmi, Cedric Manlhiot, Alejandro A. Floh, Fraser Golding, William G. Williams, Brian W. McCrindle

Bibliographic record

VenueCongenital Heart Disease · 2010
Typearticle
Languageen
FieldMedicine
TopicCardiac Structural Anomalies and Repair
Canadian institutionsUniversity of TorontoHospital for Sick Children
Fundersnot available
KeywordsMedicinePresentation (obstetrics)HypoplasiaVentricleDuctus arteriosusCardiologyInternal medicineDouble outlet right ventricleSurgery

Abstract

fetched live from OpenAlex

BACKGROUND: Double outlet left ventricle (DOLV) is a rare cardiac malformation in which both great arteries originate from the morphological left ventricle. There are limited data regarding the anatomical spectrum, characteristics and outcomes of DOLV. METHODS: All patients with DOLV between 1960 and 2008 were identified. Patients' presentation, anatomy, surgical history, and outcomes were recorded. Kaplan-Meier estimates were used to describe time-related survival and freedom from surgical intervention. RESULTS: There were 19 patients with DOLV during the study period, 14 of whom were male (74%). Median age at presentation was 2 days (birth--5.5 years). The most prominent associated cardiac morphologies (in addition to DOLV) were atrial septal defects (14, 74%), ventricular septal defects (13, 68%), right ventricular hypoplasia (12, 63%), and patent ductus arteriosus (15, 80%). At presentation, nine patients (47%) were cyanosed, nine (42%) had cardiomegaly, and all had some degree of right ventricular dysfunction. Of the 19 patients, seven underwent biventricular repairs, nine underwent univentricular palliations, one had only palliative care, and two were seen for consultation only. There were six deaths in this series, five were cardiac in nature (one due to genetic syndrome). Five-year survival after presentation for both biventricular and univentricular repairs was 70-75% (P= 0.80). Most surviving patients had residual cardiac abnormalities at last follow-up despite surgical repair. DISCUSSION: DOLV is a rare cardiac malformation associated with high mortality and guarded outcomes from residual lesions.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.264
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations19
Published2010
Admission routes1
Has abstractyes

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