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Record W1491197627

Nutrigenomics, Popular Representations and the Reification of "Race"?

2008· article· en· W1491197627 on OpenAlex
Timothy Caulfield

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueHealth law review · 2008
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicNutrition, Genetics, and Disease
Canadian institutionsnot available
Fundersnot available
KeywordsRace (biology)NutrigenomicsReification (Marxism)Context (archaeology)SociologyEthnic groupGenetic genealogyRelevance (law)Perspective (graphical)EpistemologyPopulationPoliticsBiologyPolitical scienceGeneticsAnthropology
DOInot available

Abstract

fetched live from OpenAlex

I. Introduction The concept of has long been controversial. Not only is it a profoundly socially divisive notion, its relevance to biomedical research community remains contested. Few in scientific community would claim that centuries old, socially constructed categories of race--such as black, white, Asian--have true biological significance. The human species cannot be categorized along clear biological demarcations. Indeed, we humans are a remarkable genetically homogenous lot. And more we learn about subtle genetic variations that make each of us biologically unique, more it seems that social concept of is a biological fiction. (1) That said, there are, no doubt, subtle and identifiable genetic differences between discrete populations based on geographic origin. Understanding these differences can facilitate genetic research and, ultimately, disease treatment and prevention. And an exploration of difference does not lead, inextricably, to social dilemmas. As noted by one scientist: Depending on how we use this information, potential exists to describe simultaneously our similarities and differences without reaffirming old prejudices. (2) But it is easy to slip from a discussion of genetic variation between populations to use of biologically crude and politically and historically complex notion of race. As such, researchers, clinicians and entities that provide genetic services to public must be careful how they communicate genetic information. In this paper, I explore concept of race in context of emerging field of It has been said that the assumption of real genetic markers that distinguish one ethnic group from another is at philosophical heart of nutrigenomics. (3) Given this perspective, might marketing of nutrigenomic services and products facilitate re-legitimization of race as a biological concept? (4) II. Nutrigenomics, Genetics and Race The current value of nutrigenomic testing has been questioned by many, including popular press, (5) some in scientific community, (6) government agencies, (7) and non-governmental organizations. Despite this apprehension, some companies already market nutrigenomic tests directly to public and more will likely follow. (8) The business strategy for these companies varies, but many already offer nutrigenomic testing to public. As suggested on one company's website, aim of testing is to provide personalized health and nutrition recommendations based on an individual's diet, lifestyle and unique genetic profile. (9) The website for this company goes on to suggest that nutrigenomic testing will help public develop a gene-based road map to health. (10) As part of marketing of nutrigenomic testing, it seems likely or even inevitable that race will be used, either explicitly or implicitly, as a marketing tool. (11) The scientific literature that surrounds nutrigenomics often refers to populations from Africa, Asia, and Europe. (12) At least one genetic testing company, DNA Direct, already advertises on their website for testing based on ethnic risk. (13) This is because genetic variations that may cause individuals to metabolize food differently can roughly correspond to broad social categories of race. Most Northern Europeans, for instance, can drink milk while many from Southeast Asian cannot. (14) This kind of geographically based variation can be found in other areas of genetic research, such as pharmacogenomics. (15) Indeed, many of emerging large-scale population studies are specifically designed to identify gene variations within and between sub-populations. (16) It is hoped that this research will lead to an understanding of how members of certain sub-populations may have genetic characteristics relevant to health; be it a predisposition to certain diseases, capacity to respond more effectively to a certain pharmaceutical, or ability to metabolize caffeine in a particular manner. …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.708
Threshold uncertainty score0.198

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.326
Teacher spread0.296 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it