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Record W1502775790 · doi:10.4088/jcp.13ac08691

Decision Making and Antipsychotic Medication Treatment for Youth With Autism Spectrum Disorders: Applying Guidelines in the Real World

2013· article· en· W1502775790 on OpenAlexaff
Stephanie H. Ameis, Patricia Corbett-Dick, Lynn Cole, Christoph U. Correll

Bibliographic record

VenueThe Journal of Clinical Psychiatry · 2013
Typearticle
Languageen
FieldNeuroscience
TopicAutism Spectrum Disorder Research
Canadian institutionsHospital for Sick ChildrenSickKids FoundationCentre for Addiction and Mental HealthUniversity of Toronto
FundersGenentechHealth Resources and Services AdministrationSunovionTeva Pharmaceutical IndustriesMassachusetts General HospitalPfizerEli Lilly and CompanyBristol-Myers SquibbAstraZenecaAutism SpeaksH. Lundbeck A/SU.S. Department of Health and Human Services
KeywordsIrritabilityAripiprazoleRisperidoneAutismAggressionPsychologyPsychiatryAntipsychoticAutism spectrum disorderClinical psychologyDevelopmental psychologySchizophrenia (object-oriented programming)Cognition

Abstract

fetched live from OpenAlex

Article Abstract Because this piece does not have an abstract, wehave provided for your benefit the first 3 sentences of the fulltext. Autism spectrum disorder (ASD) is a diagnosis that is characterized by varying degrees of (1) impairment in social reciprocity, (2) impairment in social communication,and (3) repetitive, restrictive, stereotyped patterns of interests, activities, and behaviors. While ASD prevalence varies across regions, recent prevalence rates range from 1:88 children in the United States to 1:160 children worldwide. Currently, only 2 atypical antipsychotics, risperidone (in 5- to 16-year-olds) and aripiprazole (in 6- to 17-year-olds),are approved by the US Food and Drug Administration (FDA) for treatment of significant irritability (aggression toward others, deliberate self-injuriousness, temper tantrums, and labile moods) associated with ASD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.051
metaresearch head score (Gemma)0.159
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.051
Threshold uncertainty score0.271

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0510.159
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.001
Science and technology studies0.0020.002
Scholarly communication0.0060.004
Open science0.0020.004
Research integrity0.0060.008
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.130
GPT teacher head0.454
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2013
Admission routes1
Has abstractyes

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