A short period of visual deprivation at birth triggers long-lasting crossmodal reorganization of the occipital cortex in humans
Why this work is in the frame
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Bibliographic record
Abstract
The study of sensory deprivation is a striking model to reveal the role experience plays in sculpting the functional architecture of the brain. Here we used functional Magnetic Resonance Imaging to characterize brain responses to auditory stimuli in 11 adults who had been deprived of all patterned vision at birth by dense congenital cataracts in both eyes until they were removed surgically at 9 to 238 days of age. When compared to a control group with typical vision, the cataract-recovery group showed enhanced auditory-driven activity in two focal bilateral visual regions (the superior occipital gyrus and the cuneus) classically considered retinotopic. The crossmodal activation of occipital regions correlated neither with visual acuity nor with the duration of deprivation in the cataract-recovery group. A combination of dynamic causal modeling with Bayesian model selection indicated that this auditory-driven activity in the occipital cortex was better explained by direct cortico-cortical connections with primary auditory cortex than by subcortical reorganizations. These results demonstrate that a short period of visual deprivation during the early sensitive period of brain development leads to enduring large-scale crossmodal reorganization of the brain circuitry typically dedicated to vision. Meeting abstract presented at VSS 2015
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it