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Record W1508567086

INFLUENCE OF ESTROGEN ON MUSCLE PLASTICITY

2011· article· en· W1508567086 on OpenAlexaff
Peter M. Tiidus

Bibliographic record

VenueRedalyc (Universidad Autónoma del Estado de México) · 2011
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMuscle metabolism and nutrition
Canadian institutionsWilfrid Laurier University
Fundersnot available
KeywordsPlasticityEstrogenSkeletal muscleNeurosciencePhysical medicine and rehabilitationMedicineInternal medicinePsychologyPhysics
DOInot available

Abstract

fetched live from OpenAlex

"Estrogen and hormone replacement therapy (HRT) have been demonstrated to have significant benefits to metabolic health and skeletal muscle function in animal models. More recently these benefits have also been reproduced in post-menopausal human females. Estrogen and HRT will diminish exercise induced muscle damage and inflammation via stabilizing effects on muscle membranes and calcium channels. Estrogen and HRT will also enhance muscle repair and augment muscle size via effects on satellite cell activation and proliferation. In addition estrogen and HRT will augment muscle strength through direct action on myosin which will enhance myosin strong binding during muscular contraction. These benefits could be important in the longer term maintenance of health, muscle functioning and independent living in older post-menopausal females. The use of HRT should be considered in some of these individuals in the context of the overall health advantages versus drawbacks this population."

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.587
Threshold uncertainty score0.786

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.220
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations9
Published2011
Admission routes1
Has abstractyes

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