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Record W1515390229 · doi:10.1017/cbo9780511722240.177

Blastomycosis

2008· book-chapter· en· W1515390229 on OpenAlexaboutno aff
Peter G. Pappas

Bibliographic record

VenueCambridge University Press eBooks · 2008
Typebook-chapter
Languageen
FieldMedicine
TopicFungal Infections and Studies
Canadian institutionsnot available
Fundersnot available
KeywordsBlastomycosisBlastomyces dermatitidisOutbreakGeographyDimorphic fungusVegetation (pathology)ArchaeologyBiologyMedicinePathology

Abstract

fetched live from OpenAlex

Blastomycosis is a systemic pyogranulomatous disease caused by the thermally dimorphic fungus Blastomyces dermatitidis . The disease is endemic to parts of the midwestern and southcentral United States and Canada, although blastomycosis has been reported worldwide, including isolated reports from Africa and Central and South America. Within the United States and Canada, the disease is concentrated in areas along the Mississippi and Ohio River basins and the Great Lakes. In endemic areas, small point-source outbreaks of blastomycosis have been associated with recreational and occupational activities occurring in wooded areas along waterways. Current evidence indicates that B. dermatitidis exists in warm moist soil enriched by organic debris, including decaying vegetation and wood. Most infections with B. dermatitidis occur through inhalation of aerosolized spores, although infection through direct inoculation has been reported rarely. Primary infections are usually asymptomatic or may result in a self-limited flulike illness. Hematogenous dissemination of organisms from the lung can result in extrapulmonary manifestations. Blastomycosis is usually recognized as a chronic, indolent systemic fungal infection associated with various pulmonary and extrapulmonary manifestations. Pulmonary blastomycosis usually manifests as a chronic pneumonia syndrome characterized by productive cough, chest pain, hemoptysis, weight loss, and low-grade fever. There are no distinguishing radiologic features of pulmonary blastomycosis, although one or more fibronodular infiltrates or mass lesions with or without cavitation are common, often mimicking other granulomatous diseases or bronchogenic carcinoma. Hilar adenopathy and pleural effusions are uncommon. Rarely, diffuse pulmonary infiltrates consistent with adult respiratory distress syndrome may occur secondary to blastomycosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.036
Threshold uncertainty score0.122

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0360.013

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.207
Teacher spread0.179 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2008
Admission routes1
Has abstractyes

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Same venueCambridge University Press eBooksSame topicFungal Infections and StudiesFrench-language works237,207