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Record W1528798818 · doi:10.1002/9781119006039.ch16

PHYTOTHERAPEUTICS FOR CANCER THERAPY

2015· other· en· W1528798818 on OpenAlexaff
Daniel Sze, Hao Liu, Maureen Boost, Raimond Wong, Stephen M. Sagar

Bibliographic record

Venuenot available
Typeother
Languageen
FieldMedicine
TopicFungal Biology and Applications
Canadian institutionsMcMaster University
Fundersnot available
KeywordsCancerMedicineLentinulaClinical trialPharmacologyTraditional medicineOncologyBiologyInternal medicineMushroom

Abstract

fetched live from OpenAlex

This chapter examines some of the recent evidence-based scientific information about the contribution of phytotherapeutics for effective cancer management with particular emphasis on results of human clinical trials. It discusses the clinical evidence of effectiveness of phytotherapeutics mainly in relation to the anticancer mechanisms through natural killer (NK) cell enhancement. NK cells play an important role in anticancer immunomodulation. Two commonly used phytotherapeutics, the medicinal mushrooms Lentinula edodes mycelia and Ganoderma lucidum, have been found to elicit their anticancer functions by regulating NK cells. If effects on both NK numbers and toxicity are taken into account, the recommended phytotherapy strategies appear to be Hochu-ekki-to, Shenqi Fuzheng Injection (SFI), and Aidi Injection. The chapter highlights the importance of careful documentation of the clinical effects for both overall survival and quality of life, in relation to potential mechanisms of action for further evidence-based use of selected cancer phytotherapeutics.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.009
Threshold uncertainty score0.996

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.085
GPT teacher head0.394
Teacher spread0.309 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2015
Admission routes1
Has abstractyes

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