Abstract 19033: Hyperoxia Reduces Oxygen Consumption in Children With Pulmonary Hypertension
Bibliographic record
Abstract
Background: High inspired oxygen concentration (FiO2) and inhaled nitric oxide (iNO), either alone or in combination, are administered to test pulmonary vasoreactivity in children. Oxygen consumption (VO2) cannot be measured accurately with conventional methods if the inspired FiO2 >0.85 and it is usually assumed that (VO2) does not change with hyperoxia or iNO. Hypothesis: We hypothesised that an inspired FiO2 >0.85 would change VO2 compared with VO2 in room air (RA) and iNO administered with room air and could influence the accuracy of flow calculations using the direct Fick’s equation. Methods: We reviewed retrospectively the cardiac catheterization data obtained between 2009-14 in children with pulmonary hypertension (PH) without cardiac shunts and cardiac output (CO) measured by thermodilution in 3 conditions of RA, with an FiO2 >0.85 and iNO in RA. VO2 was calculated using the Fick equation CO= VO2 / arterial-venous oxygen content difference. Dissolved O2 was included in the calculation. Results: Da...
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".