An integrated microchip for dielectrophoresis based characterization and manipulation of cells
Bibliographic record
Abstract
In the past, a variety of complementary techniques such as dielectrophoretic levitation, electrorotation and travelling wave dielectrophoresis (TWD) have each been individually and effectively applied in demonstrating the promising applications of DEP in the life and biological science. In this regard, however, little effort has been devoted to the development of an integrated platform that enables simultaneous such manipulations and measurements on a single microfabricated chip. In this paper we discuss the design and implementation of a single microchip (3 mm/spl times/6 mm) onto which three types of microelectrodes of similar geometric layouts but various functions were integrated. Yeast and plant protoplasts known to have well-characterized dielectric properties as test particles were used to investigate the electrokinetic behaviors for these electrodes as a function of frequency and electrode excitation mode. Several characteristic cell electrokinetic behaviors were identified, including linear conveyance, electrorotation and levitation in different regions of the frequency spectrum. The experimental observations demonstrated the feasibility and adaptability of combining the three main electrokinetic effects of DEP as a system on a single microchip platform in a compact manner.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".