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RÁPIDA CONSTRUCCIÓN DE UNA LIBRERÍA DE LOS PRODUCTOS DE CULTIVO DE 14 BACTERIAS DEL PHYLUM FIRMICUTES SIMBIONTES DEL OCTOCORAL PSEUDOPTEROGORGIA ELISABETHAE DE LA ISLA DE PROVIDENCIA (CARIBE SUR-OCCIDENTAL)

2023· article· es· W1538440716 on OpenAlexaff
Hebelin Correa, Fabrice Berrué, Bradley Haltli, Carmenza Duque, Russell G. Kerr

Bibliographic record

VenueRevista de la Academia Colombiana de Ciencias Exactas Físicas y Naturales · 2023
Typearticle
Languagees
FieldBiochemistry, Genetics and Molecular Biology
TopicMarine Sponges and Natural Products
Canadian institutionsUniversity of Prince Edward Island
Fundersnot available
KeywordsHumanitiesBiologyArt

Abstract

fetched live from OpenAlex

El presente trabajo, describe el desarrollo de una estrategia metodológica para acelerar y simplificar la detección e identificación de los compuestos producidos en cuatro medios de cultivo diferentes, por 14 bacterias del phylum Firmicutes simbiontes del octocoral Pseudopterogorgia elisabethae de la Isla de Providencia, Caribe Sur-Occidental. El proceso involucró la miniaturización de los cultivos bacterianos, la extracción en fase sólida de los productos usando la resina DiaionTM HP-20, el análisis por UPLC-MS de los mismos y finalmente la generación de una librería que permitió descartar los componentes o productos de descomposición de los medios de cultivo, además de detectar 46 compuestos producidos por el total de las bacterias y la posterior identificación de 10 de ellos, haciendo uso de la base de datos Antibase 2007TM como herramienta de derreplicación de las sustancias detectadas.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.296
Teacher spread0.288 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2023
Admission routes1
Has abstractyes

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Same venueRevista de la Academia Colombiana de Ciencias Exactas Físicas y NaturalesSame topicMarine Sponges and Natural ProductsFrench-language works237,207