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Prevalence of iron deficiency among Inuit preschool children attending childcare centres in Nunavik (632.8)

2014· article· en· W1540211248 on OpenAlexafffundabout
Huguette Turgeon O’Brien, Rosanne Blanchet, Doris Gagné, Julie Lauzière, Carole Vézina

Bibliographic record

VenueThe FASEB Journal · 2014
Typearticle
Languageen
FieldMedicine
TopicIron Metabolism and Disorders
Canadian institutionsCentre de Santé et de Services Sociaux de ChicoutimiUniversity of OttawaUniversité Laval
FundersAboriginal Affairs and Northern Development Canada
KeywordsIron deficiencySoluble transferrin receptorLethargyFerritinAnemiaMedicineHemoglobinPediatricsIron-deficiency anemiaImmunologyInternal medicinePhysiologyIron status

Abstract

fetched live from OpenAlex

In infants and children, iron deficiency (ID) can have several adverse effects on health including lethargy, alterations of immune defense mechanisms and impaired growth and cognitive development. The purpose of this study was to determine the prevalence of ID in a group of preschool Inuit children attending childcare centres in Nunavik using conventional measurements of iron status and a relatively new parameter, soluble transferrin receptor (sTfR). sTfR is especially useful in the presence of inflammation or infection. Two hundred forty‐five Inuit children aged between 11 and 54 months (mean (SD) = 25.0 (9.6) months) were recruited between 2006 and 2010 in 10 of the 14 Nunavik communities. About half of the children were male and 52.3% (n=128) were less than 24 months old at the time of the study. Sixty‐five children were excluded because they lacked one or more of the parameters under analysis, leaving 180 subjects for the assessment of iron status. ID defined either as serum ferritin <15 mg/L, sTfR >1.55 or sTfR‐ferritin index (sTfR/log ferritin) >1.5 was found in 73.2% of subjects. Anemia (hemoglobin (Hb) <110 g/L (12‐35 months old) or <112 g/L (36‐59 months old)) was present in 15% of children, while 7.2% suffered from iron deficiency anemia (IDA) (ID and C‐reactive protein (CRP) <6 mg/L), and 5% from IDA and coexisting anemia of inflammation (ID and CRP 蠅6 mg/L). Iron deficiency constitutes a significant public health problem in these Canadian Aboriginal children. Measures to improve iron intake and bioavailability are required and consumption of traditional foods rich in iron must be encouraged. Grant Funding Source : Supported by Aboriginal Affairs and Northern Development Canada & Kativik Regional Government

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.421
Threshold uncertainty score0.847

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.231
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2014
Admission routes3
Has abstractyes

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