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Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus

2000· article· en· 816 citations· W1542691850 on OpenAlex· 10.1038/77558

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.013
GPT teacher head0.284
Teacher spread
0.271 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Medicine
Topic
Virus-based gene therapy research
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
McGill UniversityUniversity of OttawaOttawa Regional Cancer Foundation
Funders
National Cancer Institute
Keywords
Oncolytic virusVesicular stomatitis virusInterferonBiologyVirusVirologyCancer researchMelanomaImmunology
Has abstract in OpenAlex
no