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OPTIMIZATION AND SENSITIVITY ANALYSIS OF AN EXTENDED DISTRIBUTED DYNAMIC MODEL OF SUPERCRITICAL CARBON DIOXIDE EXTRACTION OF NIMBIN FROM NEEM SEEDS

2010· article· en· W1544022382 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueJournal of Food Process Engineering · 2010
Typearticle
Languageen
FieldPharmacology, Toxicology and Pharmaceutics
TopicHibiscus Plant Research Studies
Canadian institutionsToronto Metropolitan UniversityUniversity of Waterloo
Fundersnot available
KeywordsSupercritical carbon dioxideComputer scienceProcess engineeringSupercritical fluid extractionMATLABSensitivity (control systems)Context (archaeology)Extraction (chemistry)Mathematical optimizationMathematicsChemistryEngineeringChromatography

Abstract

fetched live from OpenAlex

ABSTRACT In this article, supercritical extraction of nimbin from neem seeds has been studied. In order to investigate the effect of parameters on nimbin extraction yield, a partial differential equation model based on mass conservation principles. The model was solved using MATLAB software. The results were successfully validated with available laboratory experimental data. The optimum values of the operating parameters were obtained using gradient search strategy. Optimization routine was employed to maximize process profit. The optimum value of temperature, pressure, CO 2 flow rate and particle diameter were found to be 305K, 177.339 bar, 0.9660 cm 3 /min and 0.0575 cm, respectively. Finally, a sensitivity analysis was carried out on the different model parameters, and found that process profit is mostly sensitive to neem price. PRACTICAL APPLICATIONS This work uses mathematical optimization as a computational engine to arrive at the best solution for neem extraction in a systematic and efficient way. In the context of neem supercritical fluid extraction (SFE) systems, coupling optimization with suitable simulation modules opens a new avenue of possibilities. It saves money and provides economical benefits. In neem SFE process, measuring parameters and understanding the process are difficult. In this case, modeling can provide virtual environmental for operator practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.232
Threshold uncertainty score0.476

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.386
Teacher spread0.349 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it