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Record W1546321732 · doi:10.1002/jez.b.22448

The Generation of Variation and the Developmental Basis for Evolutionary Novelty

2012· review· en· W1546321732 on OpenAlexafffund
Benedikt Hallgrímsson, Heather A. Jamniczky, Nathan M. Young, Campbell Rolian, Urs Schmidt‐Ott, Ralph Marcucio

Bibliographic record

VenueJournal of Experimental Zoology Part B Molecular and Developmental Evolution · 2012
Typereview
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEvolution and Genetic Dynamics
Canadian institutionsAlberta Children’s Hospital FoundationAlberta Children's HospitalAlberta Bone and Joint Health InstituteUniversity of Calgary
FundersNatural Sciences and Engineering Research Council of CanadaNational Institutes of HealthNational Institute of Dental and Craniofacial ResearchAlberta InnovatesNational Science Council
KeywordsNoveltyEvolutionary developmental biologyAdaptation (eye)Constraint (computer-aided design)Variation (astronomy)Diversity (politics)Perspective (graphical)Cognitive scienceEvolutionary biologyComputer scienceBiologyArtificial intelligencePsychologySociologyMathematicsSocial psychologyNeuroscience

Abstract

fetched live from OpenAlex

Organisms exhibit an incredible diversity of form, a fact that makes the evolution of novelty seemingly self-evident. However, despite the "obvious" case for novelty, defining this concept in evolutionary terms is highly problematic, so much so that some have suggested discarding it altogether. Approaches to this problem tend to take either an adaptation- or development-based perspective, but we argue here that an exclusive focus on either of these misses the original intent of the novelty concept and undermines its practical utility. We propose instead that for a feature to be novel, it must have evolved both by a transition between adaptive peaks on the fitness landscape and that this transition must have overcome a previous developmental constraint. This definition focuses novelty on the explanation of apparently difficult or low-probability evolutionary transitions and highlights how the integration of developmental and functional considerations are necessary to evolutionary explanation. It further reinforces that novelty is a central concern not just of evolutionary developmental biology (i.e., "evo-devo") but of evolutionary biology more generally. We explore this definition of novelty in light of four examples that range from the obvious to subtle.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.003
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.002
Science and technology studies0.0000.005
Scholarly communication0.0020.003
Open science0.0010.001
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.289
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations123
Published2012
Admission routes2
Has abstractyes

Explore more

Same venueJournal of Experimental Zoology Part B Molecular and Developmental EvolutionSame topicEvolution and Genetic DynamicsFrench-language works237,207