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Sterile water injection for labour pain: a systematic review and meta‐analysis of randomised controlled trials

2009· review· en· W1548003736 on OpenAlexaff
Eileen K. Hutton, M. Kasperink, Marianne J. Rutten, Angela Reitsma, Bruce Wainman

Bibliographic record

VenueBJOG An International Journal of Obstetrics & Gynaecology · 2009
Typereview
Languageen
FieldMedicine
TopicMaternal and Perinatal Health Interventions
Canadian institutionsMcMaster University
Fundersnot available
KeywordsMedicinePlaceboCaesarean sectionRandomized controlled trialMeta-analysisCochrane LibraryLabor painRelative riskSterile waterMEDLINECINAHLAnesthesiaPregnancySurgeryObstetricsInternal medicineConfidence intervalPsychological intervention

Abstract

fetched live from OpenAlex

BACKGROUND: Up to one-third of labouring women will experience painful 'back labour'. Sterile water injected lateral to the lumbosacral spine is a simple and well-researched approach to this pain. OBJECTIVE: To determine if sterile water injection for low back pain compared to placebo or alternative therapy increased or decreased the rate of Caesarean section. SEARCH STRATEGY: We performed a literature search with no language restriction in four databases: the Cochrane library, EMBASE (1980-2009), Ovid Medline (1950-2009) and CINAHL (1982-2009). SELECTION CRITERIA: We included all randomised controlled trials (RCTs) of sterile water injection for labour pain that included outcomes of interest and original data. DATA COLLECTION AND ANALYSIS: We compared Caesarean section rates among women who received sterile water injection in labour with those who received either placebo treatment or another non-pharmacological treatment modality. Other outcomes included pain scores, use of regional analgesia and women's assessment of treatment. We used Revman 5 for the meta-analysis. Data were entered by one reviewer and independently cross-checked. Pooled outcomes were reported as Relative Risk (RR) or Weighted Mean Difference using Mantel-Haenszel fixed-effects model except when the I2 value >50% indicated significant heterogeneity in which case random-effects model was used. MAIN RESULTS: We included eight RCTs. The Caesarean section rate was 4.6% in the sterile water injection group and 9.9% in the comparison group (n = 828) (RR 0.51, 95% CI: 0.30, 0.87). CONCLUSION: We believe that a large RCT should be mounted to validate our findings regarding the impact of sterile water injections on mode of delivery.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.017
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (broad), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.652
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0120.017
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0190.007
Bibliometrics0.0020.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.137
GPT teacher head0.441
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations52
Published2009
Admission routes1
Has abstractyes

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