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Record W1549136413 · doi:10.1017/s1357729800058197

Population structure, inbreeding trend and their association with hip and elbow dysplasia in dogs

2001· article· en· W1549136413 on OpenAlexaboutno aff
K. Mäki, A.F. Groen, A.-E. Liinamo, M. Ojala

Bibliographic record

VenueAnimal Science · 2001
Typearticle
Languageen
FieldVeterinary
TopicVeterinary Orthopedics and Neurology
Canadian institutionsnot available
Fundersnot available
KeywordsInbreedingLabrador RetrieverBreedPurebredInbreeding depressionHip dysplasiaBiologyPopulationVeterinary medicineDemographyAnimal scienceMedicineSurgery

Abstract

fetched live from OpenAlex

Abstract The aims of this study were to examine population structure and inbreeding trend in six dog breeds in Finland and to assess the inbreeding depression for hip and elbow dysplasia. Data consisted of 289 569 dogs, of which 36 924 dogs also had a record for hip and/or elbow dysplasia screening. From the early 1980s onwards, inbreeding trends were decreasing in the Golden Retriever, the Labrador Retriever, the Rough Collie and the Rottweiler, probably as a result of importations of dogs, and somewhat increasing in the Finnish Hound and the German Shepherd. When analysed per generation, observed mean inbreeding coefficients were higher than the expected ones in each breed, indicating that breeders have not actively avoided inbreeding. As a class effect, the inbreeding level was significant only for hip dysplasia in the Labrador Retriever and the German Shepherd breeds. As a regression, inbreeding level of a dog had only a minor effect on both of the dysplasias. Hip dysplasia in the Labrador Retriever appeared to be more influenced by longer term aggregation of homozygosity (long-term inbreeding) in animals than by shorter-term inbreeding. When analysed from two data sets with a minimum of five and two ancestral generations for each dog in the data, a statistically significant association between hip dysplasia and inbreeding for the Labrador Retriever could be detected only in the former data set.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.143
Threshold uncertainty score0.261

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.287
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations43
Published2001
Admission routes1
Has abstractyes

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