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Record W1549481310 · doi:10.1002/9780470613214.ch12

Radiation Biology of Targeted Radiotherapy

2010· other· en· W1549481310 on OpenAlexaff
David Murray, Michael Weinfeld

Bibliographic record

Venuenot available
Typeother
Languageen
FieldMedicine
TopicEffects of Radiation Exposure
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsRadioresistanceBystander effectRadiobiologyDNA damageRadiation therapyDose rateDose fractionationLow Dose RadiationRadiosensitivityDNA repairAdaptive responseCancer researchBiologyDNAComputational biologyNuclear medicineMedicineMedical physicsCancerGeneticsImmunologyInternal medicine

Abstract

fetched live from OpenAlex

This chapter contains sections titled: Introduction Targeted Radionuclide Therapy: Concepts Radiation-Induced DNA Damage Cellular DNA Damage Surveillance–Response Networks Mammalian DNA-Repair Pathways Modes of Cell Death Following Radiation Exposure Conventional Models for Cell Survival Curves, Fractionation, and Dose-Rate Effects Low-Dose Hyperradiosensitivity-Increased Radioresistance Inverse Dose-Rate Effects Cross fire The Radiobiological Bystander Effect The Adaptive Response A Possible Contribution from Low-Dose Radiobiological Mechanisms to TRT Tumor Responses? Use of Radionuclides Other Than β-Particle Emitters Role of Tumor Hypoxia and Fractionation Effects Summary and Future Directions Acknowledgments References

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.101
Threshold uncertainty score0.981

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0200.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.280
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2010
Admission routes1
Has abstractyes

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