RBC Storage Effect on Coagulation, Microparticles and Microchimerism in Critically Ill Patients
Bibliographic record
Abstract
Abstract : The study aims include investigating specific mechanisms of adverse effects related to RBC storage age in critically ill patients. IRB approvals for the clinical sites participating in this study have been approved, and patient enrollment began in March 2011. Thus far, we have enrolled 37 patients, from whom samples have been collected, processed, shipped from Canada to San Francisco. We have begun HLA typing and this has been completed for 10 patients Day 0 samples so far. As there were delays in initiation of collecting patient samples, we have not begun coagulation and microparticle testing on the patient samples yet. Optimization work for the microparticle studies have built on related NIH-funded studies of in vitro properties of microparticles, refining the list of activation markers to be tested. The tests of patient samples will be performed in batches once enough samples have been obtained to minimize batch-to-batch variability in the testing results.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".