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Record W1562937060 · doi:10.2166/wqrj.2001.015

Endocrine Disruption and Human Reproductive Effects: An Overview

2001· article· en· W1562937060 on OpenAlexaboutno aff
Warren G. Foster

Bibliographic record

VenueWater Quality Research Journal · 2001
Typearticle
Languageen
FieldEnvironmental Science
TopicEffects and risks of endocrine disrupting chemicals
Canadian institutionsnot available
Fundersnot available
KeywordsEndocrine systemEnvironmental healthReproductive healthHuman healthPopulationEpidemiologyBiologyPhysiologyMedicineEndocrinologyHormone

Abstract

fetched live from OpenAlex

Abstract Humans of all ages interact with their environment on a daily basis and are thus exposed to a variety of both man-made and naturally occurring chemicals through the air they breath, the water they drink and the food they eat. The potential for exposure to environmental contaminants to impact the function of the reproductive system and affect normal development of the reproductive tract has become an area of increasing concern at all levels of society. Environment Canada and Health Canada jointly organized a workshop to review the current state of knowledge on endocrine disrupting compounds (EDCs) and to establish a national science agenda on the scientific assessment of EDCs. This report summarizes the key scientific literature pertaining to the role of EDCs in a number of selected human reproductive/developmental outcomes. Change in the frequency of health outcome trends, epidemiological evidence of an association between the health outcome of concern and exposure to EDCs, and mechanistic evidence of receptor-mediated effects were the criteria used to evaluate the strength of the evidence. While it cannot be concluded that EDCs cause reproductive effects in the general Canadian population, the weight of evidence provides cause for continued concern.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.024
Threshold uncertainty score0.047

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0040.004
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.132
GPT teacher head0.518
Teacher spread0.386 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2001
Admission routes1
Has abstractyes

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