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Record W1568303946

Gene Life S.A.-Paris

2010· article· en· W1568303946 on OpenAlexaboutno aff
Tom Morris, Cynthia M. Pavett

Bibliographic record

VenueJournal of the International Academy of Case Studies · 2010
Typearticle
Languageen
FieldMedicine
TopicBiotechnology and Related Fields
Canadian institutionsnot available
Fundersnot available
KeywordsTest (biology)ExpatriateCorporationManagementSociologyMarketingPublic relationsBusinessPolitical scienceLawFinanceEconomics
DOInot available

Abstract

fetched live from OpenAlex

INTRODUCTION in Paris ... chestnuts in blossom ... holiday tables under the sun ... or so the song goes. But on that cold, rainy April evening, it was just plain miserable. That would also accurately describe the mood of John Williams, an American expatriate who had been living and working in Paris for just over three months. He still struggled with the language and the unfathomable bureaucracy. Worse yet, he was totally frustrated by his lack of ability to make anything positive happen at work. As he walked along the Seine on his way home from a disastrous few days at the office, he wondered how he was ever going to get the cooperation and commitment he needed to successfully market Gene Life's latest product. Gene Life Corporation It was only a short time ago that a group of genetic scientists from the Boston area formed a privately held company to focus on medical applications of genetic sequencing. All of the company founders were research physicians who had been associated with large universities in and around Boston. Since most of the founders were preeminent in their fields, obtaining venture capital was not difficult. The group was particularly interested in developing a genetic test for type II diabetes. This interest was based not only on their expertise but also the results of market surveys sponsored by the American Medical Association. It was clear that physicians were extremely interested in purchasing a potential test that could help in the diagnosis of type II diabetes. But, there was a limit on how much they were willing to pay. Unfortunately, Gene Life's first iteration of a user-friendly test kit could not be sold for any less than $3,500. Given the feedback from early marking attempts, physicians and hospitals considered the cost prohibitive. A year later, the research team discovered an innovative method to produce a test kit that could be sold to for around $500. After extensive testing, which produced very accurate diagnostic results, Gene Life started marketing the kit to physicians and hospitals in the United States. It was an immediate success, and the former small research company was immediately thrust into the competitive world of pharmaceutical manufacturing, marketing and sales. They brought in state of the art manufacturing specialists, built an extremely efficient manufacturing facility to keep costs low. This supported their cost leader marketing strategy and discouraged competition. The venture capital partner conducted an extensive marketing survey and concluded that it was in the best interest of all parties to take the company public. The IPO was managed by the Bank of Boston and resulted in $52 million in new equity ownership capital. Gene Life could now afford to bring their product to the international market. John Williams' Background Because of his unusual background, John Williams was brought in to Gene Life shortly after its inception. Right after high school, John decided not to go to college but rather worked for a construction company that immediately sent him to rural Quebec to build oil pipe lines. He eventually attained the position of crew chief where he managed up to thirty French-speaking Canadians as well as Polish-immigrant workers. However, he wanted more out of life and returned to the U.S. to attend Boston University. After graduating with a degree in biochemistry, John took a job with a large pharmaceuticals company. Three years of tedious, slow moving research led him to the conclusion that he was really more interested in the business aspects of the industry than the science. Hence, he left the job and earned his MBA at Harvard University. Upon completion of his degree, he ran into one of his undergraduate professors at a coffee shop in Fanuli Hall. Dr. Morton, who was one of the founding members of Gene Life, talked extensively about the company, its product and its difficulty in finding a competent manager who both understood genetic science and had the ability to effectively manage people. …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.222
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.337
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2010
Admission routes1
Has abstractyes

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