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Record W1569299273 · doi:10.1103/physreve.74.051903

Subgraph ensembles and motif discovery using an alternative heuristic for graph isomorphism

2006· article· en· W1569299273 on OpenAlexafffund
Kim Baskerville, Maya Paczuski

Bibliographic record

VenuePhysical Review E · 2006
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBioinformatics and Genomic Networks
Canadian institutionsPerimeter InstituteUniversity of Calgary
FundersInstitut Périmètre de physique théoriqueBoettcher Foundation
KeywordsCombinatoricsBipartite graphMathematicsSubgraph isomorphism problemGraphZipf's lawDiscrete mathematicsComputer science

Abstract

fetched live from OpenAlex

A heuristic based on vertex invariants is developed to rapidly distinguish nonisomorphic graphs to a desired level of accuracy. The method is applied to sample subgraphs from an Escherichia coli protein interaction network, and as a probe for discovery of extended motifs. The network's structure is described using statistical properties of its N-node subgraphs for N<or=14. The Zipf plots for subgraph occurrences are robust power laws that do not change when rewiring the network while fixing the degree sequence--although many specific subgraphs exchange rank. The exponent for the Zipf law depends on N. Studying larger subgraphs highlights some striking patterns for various N. Motifs, or connected pieces that are overabundant in the ensemble of subgraphs, have more edges, for a given number of nodes, than antimotifs and generally display a bipartite structure or tend toward a complete graph. In contrast, antimotifs, which are underabundant connected pieces, are mostly trees or contain at most a single, small loop.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.618
Threshold uncertainty score0.459

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.284
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations31
Published2006
Admission routes2
Has abstractyes

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