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Record W1578488705 · doi:10.1089/jamp.2013.1118

Effect of Electrostatic Charge on Deposition of Uniformly Charged Monodisperse Particles in the Nasal Extrathoracic Airways of an Infant

2014· article· en· W1578488705 on OpenAlexafffundabout
Mehdi Azhdarzadeh, Jason S. Olfert, Reinhard Vehring, Warren H. Finlay

Bibliographic record

VenueJournal of Aerosol Medicine and Pulmonary Drug Delivery · 2014
Typearticle
Languageen
FieldMedicine
TopicInhalation and Respiratory Drug Delivery
Canadian institutionsUniversity of Alberta
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsDeposition (geology)AerosolCharged particleParticle depositionParticle sizeRange (aeronautics)Particle (ecology)ChemistryElectric chargeVolumetric flow rateJet (fluid)Materials scienceAtomic physicsAnalytical Chemistry (journal)MechanicsPhysicsComposite materialIonChromatography

Abstract

fetched live from OpenAlex

BACKGROUND: The fraction of inhaled particles depositing in the nasal extrathoracic airways determines the amount of particles delivered to the lungs of infants. Electrostatic charge on particles can affect this deposition, and for this reason, deposition of charged aerosol particles in the Alberta Idealized Infant nasal geometry is examined. METHODS: Charged aerosol particles were generated via Plateau-Rayleigh jet breakup atomization with induction charging. Nasal deposition was measured by collecting particles on a filter membrane at the inlet and outlet of the airway and measuring their mass with an ultramicrobalance. The experiments were carried out using monodisperse, uniformly charged particles with aerodynamic diameters of 3-6 μm at two flow rates of 7.5 and 15 L/min, for a charge range of 0-10,000 e per particle. RESULTS: Electrostatic charge effects are largest for the lowest flow rate, smallest particle size, and highest charge level, with deposition in this case being approximately three times that for neutral particles. Higher flow rates and larger particle size result in much weaker electrostatic effects, with even the highest charge levels giving only a few percent higher deposition for the largest particle size and flow rate considered in this study. A dimensionless empirical relation based on the experimental data was developed for predicting deposition of charged particles in the idealized infant airway. CONCLUSION: Electrostatic charge on inhaled aerosol particles has only a minor effect on deposition for large particles at higher flow rates, because in this case inertial impaction dominates deposition. However, for particles with low inertia, for example, small particles or low flow rates, large values of electrostatic charge strongly increase nasal deposition in the present infant extrathoracic airway.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.273
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations22
Published2014
Admission routes3
Has abstractyes

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