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Record W1591507324 · doi:10.1007/978-0-387-33419-6_14

Rebooting the Genome

2006· book-chapter· en· W1591507324 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEvolutionary Bioinformatics · 2006
Typebook-chapter
Languageen
FieldAgricultural and Biological Sciences
TopicChromosomal and Genetic Variations
Canadian institutionsQueen's University
Fundersnot available
KeywordssortTheoretical physicsComputer sciencePhysicsMathematicsArithmetic

Abstract

fetched live from OpenAlex

With the notable exceptions of Butler and Miescher, in the nineteenth century the information concept as applied to biological molecules did not extend to information error and the need for its detection and correction (see Chapter 2). Miescher in 1892 thought that: “Sexuality is an arrangement for the correction of these unavoidable stereometric architectural defects in the structure of organized substances” (see Chapter 3). While referring to “left handed coils” being “corrected by right-handed coils,” at that timc he was unable to relate this to “nuclein,” a new substance he had discovered, later known as DNA. However, he appreciated that correction would require some sort of yardstick (i.e. “right hand coils”) to permit the fact of error in a molecule of interest (i.e. “eft hand coils”) to be detected, and then appropriately corrected.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.646
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.180
Teacher spread0.165 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it