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Record W1593265699 · doi:10.5772/25854

Preterm Birth and Long-Term Pulmonary Function

2012· book-chapter· en· W1593265699 on OpenAlexaff
Indra Narang, Amal Al-Naimi

Bibliographic record

VenueInTech eBooks · 2012
Typebook-chapter
Languageen
FieldMedicine
TopicNeonatal Respiratory Health Research
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsLungAnatomyGestationMesenchymeBiologyConnective tissueEmbryogenesisPathologyEmbryoMedicinePregnancyCell biologyInternal medicine

Abstract

fetched live from OpenAlex

To understand the pathophysiology and the outcome of chronic lung disease of infancy, it is essential to understand normal lung development and the host of cofactors that will interfere with both antenatal and postnatal lung development. Lung growth starts in utero and continues to early adolescence going through different phases The embryonic phase, between the 4 th and 7 th week, begins with the formation of a groove in the ventral lower pharynx and a bud at the lower part of the groove. After further elongation and subdivision of the bud, the two main bronchi are formed. Between the 7 th and 16 th week of gestation, known as the pseudoglandular phase, the air conducting trees continue to subdivide to form the terminal bronchioles. During the canalicular phase from the 17 th to the 26 th week of gestation, airway branching is complete with the formation of the primitive saccules. It is also during this phase that the cuboidal epithelium lining the saccules differentiates into type I and type II pneumocytes with concomitant increases in peripheral mesenchyme vascularization. From 27 weeks onwards, during the saccular phase, the lung will begin to prepare for birth with thinning of the connective tissue, secondary septation subdividing the sacculi into smaller subunits or alveoli and the presence of a single capillary layer characteristic of mature alveoli Alveoli continue to increase in number until and beyond birth. At 29 weeks gestation, there are approximately 30 million alveoli and this will increase to some 150 million alveoli by term, one third to half the adult number

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.978
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.335
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2012
Admission routes1
Has abstractyes

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