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Effects of Canola and Vegetable Oil Blends on Reactive Hyperemia Index (RHI) in Adults at Risk for Metabolic Syndrome (MetS)

2015· article· en· W1593368430 on OpenAlexaff
Sheila G. West, Cindy E McCrea, Penny M. Kris‐Etherton, Xioran Liu, Jennifer Fleming, David J.A. Jenkins, Philip W. Connelly, Benoı̂t Lamarche, Patrick Couture, Peter J.H. Jones

Bibliographic record

VenueThe FASEB Journal · 2015
Typearticle
Languageen
FieldMedicine
TopicNutritional Studies and Diet
Canadian institutionsUniversity of ManitobaUniversité LavalSt. Michael's Hospital
Fundersnot available
KeywordsCanolaPolyunsaturated fatty acidCrossover studyAnimal scienceMedicineFood scienceChemistryBiologyFatty acidBiochemistry

Abstract

fetched live from OpenAlex

We evaluated the effects of 5 dietary oils on RHI: corn/safflower oil (69.3% LA, 17.6% MUFA), canola oil (62.8% MUFA, 29.3% PUFA: 19.5% LA, 10% ALA), high‐oleic canola oil (72% MUFA, 17% PUFA: 15% LA, 2% ALA), high‐oleic canola oil with DHA (63.8% MUFA, 13% LA, 6% DHA), and flax/safflower oil (69.4% PUFA: 37.5% LA, 32% ALA, 17.9% MUFA). We conducted a multi‐center, randomized, 5‐period crossover, controlled feeding study. RHI was measured after isocaloric, heart‐healthy diets containing one of 5 oils for 4 weeks, followed by >2 week break. In adults at risk of MetS, there was no significant treatment effect for RHI, an index of endothelial function. There was a treatment x period interaction (p=0.03). Because of known menstrual changes in RHI, we made an a priori decision to separately analyze effects excluding premenopausal women. In this subsample (n = 85), there was a significant treatment effect (P=0.048). RHI on the corn/safflower diet was significantly greater than on the flax/safflower diet (mean RHI=2.2±0.1 vs. 1.9 ±0.1 P=0.038). No other differences were significant.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.246
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2015
Admission routes1
Has abstractyes

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