4V microfluidic platform for biological manipulation with glycine, glutamate, GABA and acetylcholine
Bibliographic record
Abstract
This paper presents a new system dedicated for in vitro study of neuron networks to mimic neurodegenerative diseases. It is designed to modulate neurotransmitter concentration in a local area of the neuron network with dielectrophoretic manipulations. Particle motion was observed at low voltages down to 4 V peak to peak. Different concentrations of neurotransmitters close to brain concentrations were used with GABA, Glutamate, Acetylcholine and Glycine. The conductivity of manipulated liquid composed of artificial cerebrospinal fluid and neurotransmitters was 16.5 mS/cm. It was not significantly affected by neurotransmitter concentration change. The proposed system was tested with an 8 electrode array (EA) and further extended to a 320 EA in order to cover the back side of a 2.5 inches Petri dish for neuron culture.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".