Measurement of the Na background currents in small cells
Bibliographic record
Abstract
The authors measured the steady state Na current using the whole cell voltage clamp method in 19 ventricular cells from neonatal rats. In 12 cells they found a complex I/V relationship that showed two peaks at -46.9/spl plusmn/1.9 mV and -19.1/spl plusmn/1.6 mV and the mean amplitude of both was -5.1/spl plusmn/1.0 pA, In five cells the existence of two peaks was uncertain and the two remaining cells showed only one peak. In the I/V relationship showing two peaks both peaks were abolished by 200 /spl mu/M TTX. The I/V curves could be fitted to a model consisting of two different Na channels exhibiting window currents resulting from an overlap of the voltage range of steady state activation and inactivation. The model is also compatible with one type of Na channel showing two different modes of operation.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".