Modulation of Epithelial Cell Function by Glucocorticoids: Anti‐Inflammatory and Other Effects
Bibliographic record
Abstract
This chapter contains sections titled: Introduction Expression of inflammatory genes by epithelial cells is reduced by glucocorticoids Modulation of transcription by GR at simple GREs Inflammatory genes contain binding sites for transcriptional activators and these mediate glucocorticoid-dependent repression Nuclear events mediate transrepression Transactivation plays an important anti-inflammatory role Post-transcriptional effects and a role for glucocorticoid-dependent gene expression MKP-1, an anti-inflammatory glucocorticoid-inducible gene Other glucocorticoid-inducible genes with anti-inflammatory potential in the epithelium Effect of glucocorticoids on lipid mediator production by epithelial cells Remodelling, viruses, glucocorticoids and the epithelium Ion and other channels in the epithelium and the effect of glucocorticoids Maturation of the fetal airway epithelium Non-genomic actions of glucocorticoids Summary Acknowledgements References
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.033 | 0.006 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".