Hepatitis autoinmune en niños. Perspectivas actuales
Bibliographic record
Abstract
Hepatitis autoinmune en niños. Perspectivas actualesAutoimmune hepatitis in children.Current perspectives RESUMEN La hepatitis autoinmune es una enfermedad inflamatoria crónica progresiva del hígado de etiología desconocida.Afecta predominantemente al sexo femenino en la etapa prepuberal.Se caracteriza por presentar niveles elevados de transaminasas e inmunoglobulina G, niveles bajos del factor 4a del complemento y de IgA circulantes, autoanticuerpos en suero, prevalencia del antígeno leucocitario humano B8, haplotipos DR3 y DR4, y hepatitis de interfase en la histología.El curso puede ser fluctuante, con períodos de remisión espontánea.Se describen dos tipos de acuerdo con los autoanticuerpos hallados en suero.El mecanismo de producción del daño hepático es secundario a reacciones inmunes contra antígenos hepáticos no controladas adecuadamente por las células T reguladoras.La mayoría de los pacientes responden favorablemente al tratamiento inmunosupresor.Librada a su evolución espontánea, la enfermedad progresa hacia la destrucción hepática, por lo que, en su etapa terminal, requiere un trasplante hepático.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".