Antibacterial and Chemical Properties of Chromatographic Fractions of Acidic Metabolites from Garcinia Kola Seed Extract
Bibliographic record
Abstract
Acidic metabolites were precipitated from ethanolic extract of Garcinia kola seed and fractionated by column chromatography to obtain three fractions AM1, AM2, and AM3. Chemical test on the acidic metabolites and the fractions showed they were mainly flavonoids. In vitro antibacterial screening of the fractions showed they possessed antibacterial activity. They inhibited the growth of five human test bacterial isolates: Coliform bacilli, Escherichia coli, Salmonella spp., Staphylococcus aureus and Streptococcus spp. Their inhibition zone diameters ranged from 8 mm to 26 mm. The standard control antibiotic Ciprofloxacin gave inhibition zone diameters ranging from 18 mm to 20 mm, at the same concentration of 100 mg/ml for the same test bacteria. It was concluded that with appropriate standardization, the three fractions from the acidic metabolites of ethanolic extract of seed of Garcinia kola could effectively complement the existing antibiotics with beneficial health effect.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".