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Record W1656307105

Optimizing anthrax outbreak detection using reinforcement learning

2007· article· en· W1656307105 on OpenAlexaff
Masoumeh T. Izadi, David L. Buckeridge

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBacillus and Francisella bacterial research
Canadian institutionsMcGill University
Fundersnot available
KeywordsComputer scienceReinforcement learningMarkov decision processOutbreakReliability (semiconductor)Partially observable Markov decision processKey (lock)False alarmALARMMarkov processComputer securityMachine learningArtificial intelligenceMarkov chainRisk analysis (engineering)Markov modelEngineering
DOInot available

Abstract

fetched live from OpenAlex

The potentially catastrophic impact of a bioterrorist attack makes developing effective detection methods essential for public health. In the case of anthrax attack, a delay of hours in making a right decision can lead to hundreds of lives lost. Current detection methods trade off reliability of alarms for early detection of outbreaks. The performance of these methods can be improved by modern disease-specific modeling techniques which take into account the potential costs and effects of an attack to provide optimal warnings. We study this optimization problem in the reinforcement learning framework. The key contribution of this paper is to apply Partially Observable Markov Decision Processes (POMDPs) on outbreak detection mechanism for improving alarm function in anthrax outbreak detection. Our approach relies on estimating the future benefit of true alarms and the costs of false alarms and using these quantities to identify an optimal decision. We present empirical evidence illustrating that the performance of detection methods with respect to sensitivity and timeliness is improved significantly by utilizing POMDPs.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.010
Threshold uncertainty score0.020

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.009
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.291
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2007
Admission routes1
Has abstractyes

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Same topicBacillus and Francisella bacterial researchFrench-language works237,207