Gabapentin Treatment of Impulsive-Aggressive Behaviour
Bibliographic record
Abstract
Gabapentin is a relatively new antiepileptic agent structurally similar to gamma-aminobutyric acid (GABA), with unclear mechanisms of action and a good safety profile. It has been used in psychiatric practice, with promising results, for the treatment of several disorders (e.g. bipolar disorder, schizoaffective disorder, obsessive-compulsive disorder, social phobia, behavioral agitation in dementia). With regard to aggressive behavior, a few studies have reported significant improvement in symptoms among demented patients , while in one study it has been indicated a decrease in frequency and intensity of violent episodes in a young patient affected by intermittent explosive disorder, attention deficit hyperactivity disorder, organic mood disorder secondary to a closed head injury, simple partial seizure disorder after treatment with gabapentin (1200mg/day). We report a case of successful treatment of chronic impulsive aggressive behavior by using gababentin in a patient with severe borderline personality disorder.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.011 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".