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Diagnosis and Management of Hyperinsulinemic Hypoglycemia

2009· book-chapter· en· W166300538 on OpenAlexaboutno aff
Adrian Vella, Geoffrey B. Thompson, F. John Service

Bibliographic record

VenueEndocrine Surgery · 2009
Typebook-chapter
Languageen
FieldMedicine
TopicNeuroendocrine Tumor Research Advances
Canadian institutionsnot available
Fundersnot available
KeywordsInsulinomaHypoglycemiaMedicineHyperinsulinemic hypoglycemiaHyperinsulinismInternal medicineInsulinEndocrinologyGastroenterologyPediatricsInsulin resistance

Abstract

fetched live from OpenAlex

The first case of hyperinsulinism was reported in 1927, at the Mayo Clinic, when an orthopedic surgeon presented with episodes of severe hypoglycemia due to a malignant pancreatic islet cell tumor [1]. Following his death, postmortem extracts of liver metastases caused marked hypoglycemia when injected into laboratory animals. In 1929, Graham in Toronto performed the first curative operation for a benign insulinoma. Subsequent to the identification of insulinoma as the source of excessive insulin secretion, the recognition that food deprivation provoked hypoglycemia led to the evolution of the prolonged fast as the chief diagnostic test for hypoglycemia in the absence of a documented, spontaneous episode.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.299
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2009
Admission routes1
Has abstractyes

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