Paralysis in Nerve Agent Toxicosis in Guinea Pigs
Bibliographic record
Abstract
Since the discovery of the G-type nerve agents, there have been numerous studies of Central Nervous System (CNS) involvement in the etiology of organophosphate poisoning, notably associated with status Elipticus and/or "electrographic seizures". Brain damage from these effects has been demonstrated as "neuronal necrosis" primarily in the cortex, thalamus and hippocampus. However, despite recurring references to CNS damage, to the author's knowledge there have been no reports of long term paralysis manifested within 24 hr of nerve agent exposure. Occasional paralysis following an asymptomatic time interval of 7-14 days has been reported. This report is intended to summarize the immediate, nerve agent induced paralytic events recorded in guinea pigs (as incidental observations) during development of the Canadian Reactive Skin Decontaminant Lotion RSDL(R). Because the experiments were designed to assess the decontamination procedures, there were no apparent relationships between the amounts of agent applied and the sequellae recorded.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".