Abstract 17744: Impact of Hypertensive Crisis on Left Ventricular Systolic and Diastolic Function: Comprehensive Speckle Tracking Strain Analysis vs. Conventional Echocardiography
Bibliographic record
Abstract
Introduction: Echocardiographic strain analysis using speckle tracking is more sensitive than traditional 2-D & Doppler evaluation. The acute impact of hypertensive crisis on LV systolic and diastolic function using echocardiography is not described. Hypothesis: Hypertensive crisis induces acute impairment of LV systolic & diastolic function that may be detected using strain analysis. Methods: Thirty consecutive patients with hypertensive crisis underwent serial echocardiograms including 2D, Doppler & Speckle Tracking strain analyses at baseline & after blood pressure optimization. Results: Mean age of the patients was 53.9 ± 12.8 yrs. Most common presenting symptoms were shortness of breath (70%), chest pain (43.3%), & altered mental status (13.3%). Mean systolic & diastolic blood pressures at baseline were 193.5 ± 25.1mmHg and 106.8 ± 19.8mmHg that reduced to 142.8 ± 20.5mmHg (p<0.001) and 76.7 ± 18.4mmHg (p<0.001) respectively after therapy.Baseline and follow-up echocardiograms showed reduction in left and right atrial volumes at follow-up. There was no change in LV ejection fraction & fractional shortening at follow-up (48.5 ± 18.2 % vs. 46.7 ± 18.3 %; p=0.50 and 28.0 ± 15.2 % vs. 30.8 ± 14.4 %; p=0.22 respectively). Doppler trans-mitral E-wave and A-wave velocities & mitral E/A ratio were similar at baseline and follow-up.There was an increase in mean global longitudinal LV systolic strain (-10.4 ± 4.4 % to -12.1 ± 4.2 %; p=0.011). Peak systolic circumferential strain increased on follow-up from -6.0 ± 3.2 to -11.3 ± 5.4, p=0.03.Mean global early diastolic strain increased from -4.9 ± 2.7 to -9.4 ± 5.0, p=0.05 at follow-up. Conclusions: Our study describes the impact of hypertensive crisis on echocardipgrahic parameters of LV systolic and diastolic function using strain analysis that has never been described before. Global longitudinal & circumferential systolic strain are more sensitive at detecting subtle changes in LV systolic function in the setting of hypertensive crisis when compared to ejection fraction and fractional shortening. Echocardiographic indices of LV diastolic function (E/e', Left atrial volume and mitral DT) as well as early diastolic strain also significantly improve after therapy.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".