Bibliographic record
Abstract
Anorexia nervosa (AN) is a life-threatening eating disorder (ED) characterized by restrictive eating, the pursuit of thinness and an obsessive fear of being fat. The lifetime prevalence of AN is 0.3-1% with morality rates approximately 8-15%, higher than in any other mental illness. Unfortunately, treatment therapies have remained generally unsuccessful. Relapse is common, disordered eating patterns persistent in majority of the cases and as many as 20% remaining chronically ill. Despite the severity and chronicity of the disorder, the etiology of AN is largely unknown. Multiple theories have been developed outlining the biological, psychological and cultural factors contributing to AN pathogenesis. However, there is a growing consensus that understanding the predisposing genetic and neurobiological factors leading to AN is critical in order to improve treatment outcomes. The purpose of this mini-review is to summarize the current evidence pointing to alterations in serotonin (5-HT) and dopamine (DA) function in AN pathology. Disturbances in these neurotransmitter systems may explain the underlying genetic component and common psychiatric traits and comorbid disorders present in AN.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".