MétaCan
Menu
Back to cohort

Lower body muscle tensing is an effective countermeasure to initial orthostatic hypotension induced cerebral hypo‐perfusion upon standing from a squatted position

2012· article· en· W178400550 on OpenAlexaff
Jeremy J. Walsh, Robert F. Bentley, J. Mikhail Kellawan, Michael E. Tschakovsky

Bibliographic record

VenueThe FASEB Journal · 2012
Typearticle
Languageen
FieldMedicine
TopicHemodynamic Monitoring and Therapy
Canadian institutionsQueen's University
Fundersnot available
KeywordsMedicineCerebral perfusion pressureMiddle cerebral arteryPerfusionTranscranial DopplerAnesthesiaCardiologyBlood pressureMean arterial pressureCerebral blood flowCerebral autoregulationInternal medicineHeart rateAutoregulationIschemia

Abstract

fetched live from OpenAlex

PURPOSE to examine the effects of 5 s of lower body muscle tensing (LBMT) after rising from squat on middle cerebral artery blood velocity (MCABV) following a squat‐to‐stand protocol. METHODS Healthy subject (n =8; 24.4 ±1.9 yrs) performed a squat‐to‐stand protocol. Upon standing participants performed either no manoeuvre (Control) or LBMT which was held for 5 s. MCABV (cm/s; surrogate for cerebral perfusion) was measured with transcranial Doppler ultrasound (TCD), mean arterial pressure (MAP) via finger photoplethysmography. Cerebral blood pressure (CBP) was calculated by measuring the hydrostatic column from the heart (MAP) to the TCD probe. Cerebral vascular conductance (CVC) was calculated from MCABV and CBP. RESULTS Data are mean ±SD. The drop in MAP upon rising from squat was −15.8 ±3.9 mmHg in Control vs. −6.02 ±10.5 mmHg in LBMT, p < 0.05. This represented a 62% attenuation of hypotension via LBMT. MCABV decreased by −11.8 ±3.07 cm/s in Control vs. −3.72 ±4.48 cm/s in LBMT, P <0.05, which represents a 68% attenuation of cerebral hypo‐perfusion. CONCLUSIONS LBMT for the first 5 s upon rising from squat is an effective countermeasure for minimizing cerebral hypo‐perfusion. NSERC .

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.304
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2012
Admission routes1
Has abstractyes

Explore more

Same venueThe FASEB JournalSame topicHemodynamic Monitoring and TherapyFrench-language works237,207