MétaCan
Menu
Back to cohort
Record W1800480040 · doi:10.1016/j.fsigen.2015.08.003

52 additional reference population samples for the 55 AISNP panel

2015· article· en· W1800480040 on OpenAlexaff
A.J. Pakstis, Eva Haigh, Lotfi Cherni, Amel Ben Ammar Elgaaïed, Alison R. Barton, Baigalmaa Evsanaa, Ariunaa Togtokh, Jane E. Brissenden, Janet Roscoe, Özlem Bülbül, Gönül Filoğlu, Cemal Gürkan, Kelly A. Meiklejohn, James Robertson, Caixia Li, Yi‐Liang Wei, Hui Li, Usha Soundararajan, Haseena Rajeevan, Judith R. Kidd, Kenneth K. Kídd

Bibliographic record

VenueForensic Science International Genetics · 2015
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic diversity and population structure
Canadian institutionsThe Scarborough HospitalUniversity of Toronto
FundersOak Ridge Institute for Science and EducationOffice of Justice ProgramsNational Natural Science Foundation of ChinaU.S. Department of EnergyFederal Bureau of InvestigationNational Institute of JusticeTürkiye Bilimsel ve Teknolojik Araştırma KurumuU.S. Department of JusticeNational Science Foundation
KeywordsPopulationMassive parallel sequencingAllele frequencySingle-nucleotide polymorphismBiologyInferenceAlleleGeneticsComputational biologyStatisticsComputer scienceDNA sequencingGenotypeMathematicsGeneDemographyArtificial intelligence

Abstract

fetched live from OpenAlex

Ancestry inference for a person using a panel of SNPs depends on the variation of frequencies of those SNPs around the world and the amount of reference data available for calculation/comparison. The Kidd Lab panel of 55 AISNPs has been incorporated in commercial kits by both Life Technologies and Illumina for massively parallel sequencing. Therefore, a larger set of reference populations will be useful for researchers using those kits. We have added reference population allele frequencies for 52 population samples to the 73 previously entered so that there are now allele frequencies publicly available in ALFRED and FROG-kb for a total of 125 population samples.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.046
Threshold uncertainty score0.152

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.005
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0040.003
Science and technology studies0.0020.000
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0460.013

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.103
GPT teacher head0.309
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations43
Published2015
Admission routes1
Has abstractno

Explore more

Same venueForensic Science International GeneticsSame topicGenetic diversity and population structureFrench-language works237,207