cDNA cloning, expression and regulation analysis of goose adipose triglyceride lipase (<i>ATGL</i>) gene
Bibliographic record
Abstract
Lu, L., Wang, F., Chen, X., Yuan, H., Tian, Y., Li, J., Shen, J., Tao, Z. and Fu, Y. 2011. cDNA cloning, expression and regulation analysis of goose adipose triglyceride lipase ( ATGL ) gene. Can. J. Anim. Sci. 91: 363–369. Adipose triglyceride lipase (ATGL) has an important role in adiposome turnover in mammals. In avian species, the ATGL gene has been reported in chicken, duck, quail, turkey and parrot. We describe here the cloning and characterization of the ATGL in goose. Goose ATGL encodes a 482-amino-acid protein, which contains a “GXSXG” motif and 169-amino acid “patatin” domain. The deduced goose ATGL protein shows more than 85% identity to the reported avian species. Quantitative real-time RT-PCR analysis reveals that the goose ATGL mRNA is more highly expressed in subcutaneous fat. We also identify changes of goose ATGL mRNA expression pattern after over-feeding treatment, which may reveal that expression of ATGL in obesity is tissue-specific in goose. Moreover, we conclude that the mRNA level of ATGL can be regulated by oleic acid in goose adipocytes.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".