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Record W1819269555 · doi:10.22037/aaem.v2i2.27

The Risk of Venous Thromboembolism Associated with Oral Contraceptive; the Search Is Still On.

2014· article· en· W1819269555 on OpenAlexaff
Ali Abdalvand

Bibliographic record

VenuePubMed · 2014
Typearticle
Languageen
FieldMedicine
TopicReproductive Health and Contraception
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsGestodeneDesogestrelDrospirenoneMedicineLevonorgestrelPillEthinylestradiolEstrogenFirst generationVenous thromboembolismObstetricsGynecologyPopulationFamily planningPharmacologyPhysiologyEndocrinologyInternal medicineResearch methodologyThrombosisEnvironmental health

Abstract

fetched live from OpenAlex

few years after coming to the market, the first generation of oral contraceptive pills (OCPs) were linked to significant risk of venous throm-boembolism (VTE). This increased risk was blamed on the presence of the estrogen-like compounds in these agents. Therefore, the efforts were initiated to decrease the VTE risk of OCPs by lowering the delivered estrogen content by adding progestins such as levonorgestrel to these products, which led to production of the second generation of OCPs. Thereafter, the third generation of these agents with lower doses of progesterone-like compounds with contraceptive efficacy was released. They contain the new progestins such as Drospirenone, Norgestimate, Desogestrel and Gestodene (1-3). Baratloo et al. review article (The Risk of Venous

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.930
Threshold uncertainty score0.215

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.264
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2014
Admission routes1
Has abstractyes

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