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Record W1821013472 · doi:10.1139/p2012-088

Robust stabilization and <i>H</i><sub>∞</sub> control for discrete-time stochastic genetic regulatory networks with time delays

2012· article· en· W1821013472 on OpenAlexvenueno aff
K. Mathiyalagan, R. Sakthivel

Bibliographic record

VenueCanadian Journal of Physics · 2012
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGene Regulatory Network Analysis
Canadian institutionsnot available
Fundersnot available
KeywordsControl theory (sociology)Upper and lower boundsDiscrete time and continuous timeBounded functionInterval (graph theory)Linear matrix inequalityController (irrigation)Robust controlPhysicsApplied mathematicsComputer scienceMathematical optimizationControl (management)MathematicsNonlinear systemMathematical analysis

Abstract

fetched live from OpenAlex

This paper presents some novel results on robust stabilization and H ∞ control design for a class of uncertain discrete-time stochastic genetic regulatory networks (GRNs) with time-varying delays. The GRNs under consideration are subject to stochastic noise, time-varying, and norm bounded parameter uncertainties. By constructing a new Lyapunov–Krasovskii functional that contains some novel triple summation terms, we propose a state feedback gene controller to guarantee that the considered GRN is mean-square asymptotically stable about its equilibrium point for all admissible uncertainties. The other issue is to design a H ∞ feedback gene controller so that the GRN is robustly stable with a prescribed H ∞ disturbance attenuation level for all admissible uncertainties and for all delays to satisfy both the lower bound and upper bound of the interval time-varying delay. The obtained conditions are derived in terms of linear matrix inequalities (LMIs), which can be easily verified via the LMI toolbox. Finally, the control scheme has been implemented in a gene network model to illustrate the applicability and usefulness of the obtained results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.341
Threshold uncertainty score0.706

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.171
Teacher spread0.166 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations35
Published2012
Admission routes1
Has abstractyes

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